Frequently Used Tools in Structural Biology

  • FindMySequence - "A neural-network-based approach for identification of unknown proteins in X-ray crystallography and cryo-EM."

  • DeepTracer - "Ultra-fast, fully automated and accurate de novo macromolecular complex structure prediction and identification from 3D electron density maps using 3D deep learning."

  • BioRender.

  • ChimeraX recipes and Python functions and structures for scripting.


Links for Lab Recipes

Recommended Books

  • Blankenship, Robert E. Molecular Mechanisms of Photosynthesis. 2nd ed., Wiley Blackwell, 2014.

  • Cantor and Schimmel. Biophysical Chemistry. Freeman, 1980.

  • Duda, R.O., Hart, P.E., and Stork, D.G. Pattern Classification. 2nd ed., John Wiley & Sons, 2001.

  • Goodman, J.W. Introduction to Fourier Optics. 4th ed., W.H. Freeman, 2017.

  • Kirkland, E.J. Advanced Computing in Electron Microscopy. 2nd ed., Springer, 2010.

  • Spence, John C.H. High-Resolution Electron Microscopy. 4th ed., Oxford University Press, 2013.