Publications

(*equal contributions; #corresponding authors)

Puskar, R., Truong, C.D., Swain, K., Chowdhury, S., Chan, K.-Y., Li, S., Cheng, K.-W., Wang, T.Y., Poh, Y.-P., Mazor, Y., Liu, H., Chou, T.-F., Nannenga, B.L., and Chiu, P.-L. (2022). "Molecular asymmetry of photosynthetic supercomplex from green sulfur bacteria." Nature Communications, 13, 5824.

*Narayanan, R.P., *Procyk, J., Nandi, P., Prasad, A., Xu, Y., Poppleton, E., Williams, D.R., Zhang, F., Yan, H., #Chiu, P.-L., #Stephanopoulos, N., and #Šulc, P. (2022). "Coarse-grained simulations for the characterization and optimization of hybrid protein-DNA nanostructures." ACS Nano, 16, 14086-14096.

DeVore, K. and Chiu, P.-L. (2022). "Probing structural perturbation of biomolecules by extracting cryo-EM data heterogeneity." Biomolecules, 12, 628.

Baker, A.T., Boyd, R.J., Sarkar, D., Crespo, A.T., Chan, C.K., Bates, E., Waraich, K., Vant, J., Wilson, E., Truong, C.D., Lipka-Lloyd, M., Fromme, P., Vermaas, J., Williams, D., Machiesky, K., Heurich, M., Nagalo, B.M., Coughlan, L., Umlauf, S., Chiu, P.-L., Rizkallah, P.J., Cohen, T.S., Parker, A.L., Singharoy, A., and Borad, M.J. (2021). "ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome." Science Advance, 7, eabl8213.

Truong, C.D., Williams, D., Zhu, M., Wang, J.C.-H., and Chiu, P.-L. (2021). "Sample preparation using lipid monolayer method for electron crystallographic studies." Journal of Visualized Experiments, 177, e63015.

*Zhang, X., *Gui, L., *Li, S., *Nandi, P., Wong, D.E., Moen, D.R., Lin, H.J., #Chiu, P.-L., and #Chou, T.-F. (2021). "Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity." Biochemical Journal, 478, 3185-3204.

Nandi, P., Li, S., Columbres, R.C.A., Wang, F., Williams, D.R., Poh, Y.-P., #Chou, T.-F., and #Chiu, P.-L. (2021). "Structural and functional analysis of disease-linked p97 mutant complexes." International Journal of Molecular Sciences, 22, 8079.

Truong, C.D., Craig, T.A., Cui, G., Botuyan, M.V., Serkasevich, R.A., Chan, K.-Y., #Mer, G., #Chiu, P.-L., and #Kumar, R. (2021). "Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta." Journal of Biological Chemistry, 297, 100912.

March, K., Venkatraman, K., Truong, C.D., Williams, D., Chiu, P.-L., and Rez, P. (2021). "Protein secondary structure signatures from energy loss spectra recorded in the electron microscope." Journal of Microscopy, 282, 215-223.

Chan, K.-Y., Truong, C.D., Poh, Y.-P., and Chiu, P.-L. (2021). "Sample preparation and data collection for electron crystallographic studies on membrane protein structures and lipid-protein interaction." Methods in Molecular Biology, 2215, 247-265.

Yang, J.-Y., Williams, D., Kandiah, E., #Fromme, P., and #Chiu, P.-L. (2020). "Structural basis of redox modulation on chloroplast ATP synthase." Communications Biology, 3, 482.

Godeshala, S., Miryala, B., Dutta, S., Christensen, M.D., Nandi, P., Chiu, P.-L., and Rege, K. (2020). "A library of aminoglycoside-derived lipopolymer nanoparticles for delivery of small molecules and nucleic acids." Journal of Materials Chemistry B, 8, 8558-8572.

Chang, S.L.Y., Reineck, P., Williams, D., Bryant, G., Opletal, G., El-Demrdash, S.A., Chiu, P.-L., Ōsawa, E., Barnard, A.S., and Dwyer, C. (2020). "Dynamic self-assembly of detonation nanodiamond in water." Nanoscale, 12, 5363-5367.

Robertson, K.E., Truong, C.D., Craciunescu, F.M., Yang, J.-Y., Chiu, P.-L., Fromme, P., and Hansen, D.T. (2019). "Membrane directed expression in Escherichia coli of BBA57 and other virulence factors from the Lyme disease agent Borrelia burgdorfeni." Scientific Reports, 9, 1-15.

Steber, H.S., Gallante, C., Chiu, P.-L., and Mangone, M. (2019). "The C. elegans 3'UTRome V2: an updated genomic resource to study 3'UTR biology." Genome Research, 29, 2104-2116.

Toporik, H., Li, J., Williams, D., Chiu, P.-L., and Mazor, Y. (2019). "The structure of the photosystem I IsiA super-complex." Nature Structural and Molecular Biology, 26, 443-449.

*Aryal, R.P., *Kwak, P.B., *Tamayo, A.G., Chiu, P.-L., Walz, T., and Weitz, C.J. (2017). "Macromolecular assemblies of the mammalian circadian clock." Molecular Cell, 67, 770-782.

*Kalbermatter, D., *Chiu, P.-L., Jeckelmann, J.-M., Ucurum, Z., Walz, T., and Fotiadis, D. (2017). "Electron crystallography reveals that substrate release from the PTS IIC glucose transporter is coupled to a subtle conformational change." Journal of Structural Biology, 199, 39-45.

Leksa, N.C., Chiu, P.-L., Bou-Assaf, G.M., Quan, C., Liu, Z., Goodman, A.B., Chambers, M.G., Tsutakawa, S.E., Hammal, M., Peters, R.T., Walz, T., and Kulman, J.D. (2017). "The structural basis for the functional comparability of factor VIII and the long-acting variant rFVIIIFc." Journal of Thrombosis and Haemostasis, 15, 1167-1179.

Klara, S.S., Saboe, P.O., Sines, I.T., Babaei, M., Chiu, P.-L., DeZorzi, R., Dayal, K., Walz, T., Kumar, M., and Mauter, M.S. (2016). "Magnetically directed two-dimensional crystallization of OmpF membrane proteins in block copolymers." Journal of the American Chemical Society, 138, 28-31.

*Chiu, P.-L., *Li, X., Li, Z., Beckett, B., Brilot, A.F., Grigorieff, N., Agard, D.A., Cheng, Y., and Walz, T. (2015). "Evaluation of super-resolution performance of the K2 electron counting camera using 2D crystals of aquaporin-0." Journal of Structural Biology, 192, 163-173.

Kalbermatter, D., Jeckelmann, J.-M., Chiu, P.-L., Ucurum, Z., Walz, T., and Fotiadis, D. (2015). "2D and 3D crystallization of the wild-type IIC domain of the glucose PTS transporter from Escherichia coli." Journal of Structural Biology, 191, 376-380.

*Chiu, P.-L., *Bou-Assaf, G., Chhabra, E.S., Chambers, M.G., Liu, L., Peters, R., Kulman, J.D., and Walz, T. (2015). "Mapping the interaction between factor VIII and von Willebrand factor by electron microscopy and mass spectrometry." Blood, 126, 935-938.

Commentary in Blood: Krishnaswamy, S. (2015). "FVIII-VWF dos-à-dos." Blood, 126, 923-924.

*Hite, R.K., *Chiu, P.-L., Schuller, J., and Walz, T. (2015). "Effect of lipid head groups on double-layered two-dimensional crystals fromed by aquaporin-0." PLoS ONE, 10, e0117371.

Kowal, J., Chami, M., Baumgartner, P., Arheit, M., Chiu, P.-L., Rangl, M., Scheuring, S., Nimigean, C.M., and Stahlberg, H. (2014). "Ligand-induced structural changes in the cyclic nucleotide-modulateed potassium channel MloK1." Nature Communications, 5, 3106-3115.

Hopkins, L.E., Patchin, E.S., Chiu, P.-L., Brandenberger, C., Smiley-Jewell, S., and Pinkerton, K.E. (2014). "Nose-to-brain transport of aerosolized quantum dots following acute exposure." Nanotoxicology, 8, 885-893.

Evans, J.E., Jungjohann, K.L., Wong, P.C.K., Chiu, P.-L., Dutrow, G.H., Arslan, I., and Browning, N.D. (2013). "Visualizing macromolecular complexes with in situ liquid scanning transmission electron microscopy." Micron, 43, 1085-1090.

Chiu, P.-L., Kelly, D.F., and Walz, T. (2011). "The use of trehalose in the preparation of specimens for electron microscopy." Micron, 42, 762-772.

Paoli, E.-E., Kruse, D.E., Seo, J.W., Zhang, H., Kheirolomoom, A., Watson, K.D., Chiu, P.-L., Stahlberg, H., and Ferrara, K.W. (2010). "An optical and microPET assessment of thermally-sensitive liposome biodistribution in the Met-1 tumor model: importance of formulation." Journal of Control Release, 143, 13-22.

Chiu, P.-L., Pagel, M.D., Evans, J.E., Chou, H.-T., Zeng, X., Gipson, B., Stahlberg, H., and Nimigean, C.M. (2007). "The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 Å resolution." Structure, 15, 1053-1064.

Feature in Structure: Taraska, J.W. and Zagotta, W. (2007). "Cyclic nucleotide-regulated ion channel: Spotlight on symmetry." Structure, 15, 1023-1024.

Renault, L., Chou, H.-T., Chiu, P.-L., Hill, R.M., Zeng, X., Gipson, B., Zhang, Z.Y., Cheng, A., Unger, V., and Stahlberg, H. (2006). "Milestones in electron crystallography." Journal of Computational Aided Molecular Design, 20, 519-527.

Chiu, P.-L., Wu, C.-Y., Taso, J.-H., and Chang, F.-H. (2001). "Drug delivery through liposome by ultrasonic cavitation." Biomedical Engineering-Application, Basis, & Communications, 13, 47-52.